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Type 1 diabetes with coma

DOID MESH PheWeb

E4_DM1COMA

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E10.00, E10.01, E10.09
Hospital discharge: ICD-9 2502B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E10.00, E10.01, E10.09
Cause of death: ICD-9 2502B
Cause of death: ICD-8 $!$

1885

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1885

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Check minimum number of events None

1885

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Include endpoints None

1885

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E4_DM1COMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4

Summary Statistics

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Key figures

All Female Male
Number of individuals 1885 899 986
Unadjusted prevalence (%) 0.53 0.45 0.63
Mean age at first event (years) 33.95 32.07 35.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 8.51 [5.37, 13.48] 7.4e-20 256
15 years 0.03 4.68 [2.91, 7.51] 1.7e-10 111
5 years 0.01 7.77 [5.36, 11.26] 2.3e-27 63
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM1COMA – Type 1 diabetes with coma
GWS hits: 9

Survival analyses between endpoints

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Plot

before Type 1 diabetes with coma
after Type 1 diabetes with coma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 1 diabetes with coma

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