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Sub-endpoint used in defining T1D endpoints

PheWeb

T1D_ICD9_10

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E10
Hospital discharge: ICD-9 250
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E10
Cause of death: ICD-9 250
Cause of death: ICD-8 $!$

12233

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

11219

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Check minimum number of events None

11219

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Include endpoints None

11219

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T1D_ICD9_10

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) juvenilis

Similar endpoints

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List of similar endpoints to Sub-endpoint used in defining T1D endpoints based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 11219 5018 6201
Unadjusted prevalence (%) 3.15 2.53 3.94
Mean age at first event (years) 37.54 34.48 40.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.11 [2.60, 3.73] 1.6e-35 2340
15 years 0.01 2.03 [1.78, 2.32] 9.5e-26 1055
5 years 0.00 2.86 [2.53, 3.23] 2.8e-63 521
1 year 0.00 4.91 [4.10, 5.88] 2.3e-67 185

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_ICD9_10 – Sub-endpoint used in defining T1D endpoints
GWS hits:

Survival analyses between endpoints

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Plot

before Sub-endpoint used in defining T1D endpoints
after Sub-endpoint used in defining T1D endpoints

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Drugs most likely to be purchased after Sub-endpoint used in defining T1D endpoints

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