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Type 2 diabetes without complications

DOID EFO MESH SNOMED PheWeb

E4_DM2NOCOMP

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E11.9
Hospital discharge: ICD-9 2500A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E11.9
Cause of death: ICD-9 2500A
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

29238

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E4_DM2NOCOMP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E11

Summary Statistics

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Key figures

All Female Male
Number of individuals 29238 11928 17310
Unadjusted prevalence (%) 8.22 6.01 11.00
Mean age at first event (years) 63.11 62.05 63.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.31 [3.85, 4.83] <1e-100 7503
15 years 0.02 2.30 [2.08, 2.54] 5.5e-59 2978
5 years 0.01 4.30 [3.97, 4.66] <1e-100 2255
1 year 0.00 14.34 [12.93, 15.90] <1e-100 1651

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM2NOCOMP – Type 2 diabetes without complications
GWS hits:

Survival analyses between endpoints

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Plot

before Type 2 diabetes without complications
after Type 2 diabetes without complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 2 diabetes without complications

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