Unspecified diabetes without complications

E4_DMNASNOCOMP

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E12.9, E13.9, E14.9
Hospital discharge: ICD-9 2500C|2500X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E12.9, E13.9, E14.9
Cause of death: ICD-9 2500C|2500X
Cause of death: ICD-8 $!$

2527

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2527

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Check minimum number of events None

2527

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Include endpoints None

2527

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E4_DMNASNOCOMP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 2527 1054 1473
Unadjusted prevalence (%) 0.71 0.53 0.94
Mean age at first event (years) 53.94 52.34 55.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.34 [5.87, 9.17] 1.4e-68 525
15 years 0.02 2.54 [1.97, 3.26] 4.7e-13 165
5 years 0.01 5.97 [4.61, 7.72] 4.3e-42 165
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNASNOCOMP – Unspecified diabetes without complications
GWS hits: 4

Survival analyses between endpoints

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Plot

before Unspecified diabetes without complications
after Unspecified diabetes without complications

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Drugs most likely to be purchased after Unspecified diabetes without complications

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