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Unspecified diabetes with ophthalmic complications

DOID EFO MESH SNOMED PheWeb

E4_DMNASOPTH

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E12.3+, E13.3+, E14.3+
Hospital discharge: ICD-9 2504C|2503X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E12.3+, E13.3+, E14.3+
Cause of death: ICD-9 2504C|2503X
Cause of death: ICD-8 $!$

80

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

80

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Check minimum number of events None

80

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Include endpoints None

80

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E4_DMNASOPTH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 80 25 55
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 54.77 51.46 56.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNASOPTH – Unspecified diabetes with ophthalmic complications
GWS hits:

Survival analyses between endpoints

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Plot

before Unspecified diabetes with ophthalmic complications
after Unspecified diabetes with ophthalmic complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetes with ophthalmic complications

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