Other endocrine disorders

E4_ENDODIS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E34, E35
Cause of death: ICD-10 E34, E35

1417

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1401

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Check minimum number of events None

1401

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E4_ENDODIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Other endocrine disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1486 861 625
Unadjusted prevalence (%) 0.42 0.43 0.40
Mean age at first event (years) 29.70 29.05 30.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 6.63 [4.03, 10.91] 1.0e-13 93
15 years 0.03 3.81 [2.40, 6.02] 1.2e-8 41
5 years 0.01 7.53 [4.79, 11.82] 1.8e-18 29
1 year 0.00 14.72 [7.90, 27.42] 2.4e-17 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_ENDODIS – Other endocrine disorders
GWS hits: 1

Survival analyses between endpoints

Plot

before Other endocrine disorders
after Other endocrine disorders

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Drugs most likely to be purchased after Other endocrine disorders