Other endocrine disorders

E4_ENDODIS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E34, E35
Cause of death: ICD-10 E34, E35

1417

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1401

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Check minimum number of events None

1401

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E4_ENDODIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other endocrine disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1486 861 625
Unadjusted prevalence (%) 0.42 0.43 0.40
Mean age at first event (years) 29.70 29.05 30.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 6.63 [4.03, 10.91] 1.0e-13 93
15 years 0.03 3.81 [2.40, 6.02] 1.2e-8 41
5 years 0.01 7.53 [4.79, 11.82] 1.8e-18 29
1 year 0.00 14.72 [7.90, 27.42] 2.4e-17 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDODIS – Other endocrine disorders
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other endocrine disorders
after Other endocrine disorders

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Drugs most likely to be purchased after Other endocrine disorders

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