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Endocrine disorders, other/unspecified

DOID EFO MESH SNOMED PheWeb

E4_ENDODISNAS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E34.8, E34.9
Hospital discharge: ICD-9 2592
Hospital discharge: ICD-8 2589
Cause of death: ICD-10 E34.8, E34.9
Cause of death: ICD-9 2592
Cause of death: ICD-8 2589

549

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

541

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Check minimum number of events None

541

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Include endpoints None

541

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E4_ENDODISNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 541 361 180
Unadjusted prevalence (%) 0.15 0.18 0.11
Mean age at first event (years) 42.90 40.99 46.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.05 [0.81, 5.18] 1.3e-1 47
15 years 0.01 1.76 [0.83, 3.73] 1.4e-1 25
5 years 0.00 2.93 [1.36, 6.31] 6.0e-3 12
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDODISNAS – Endocrine disorders, other/unspecified
GWS hits: 2

Survival analyses between endpoints

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Plot

before Endocrine disorders, other/unspecified
after Endocrine disorders, other/unspecified

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Endocrine disorders, other/unspecified

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