Hypothyroidism, strict autoimmune

E4_HYTHY_AI_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not E4_HYTHY_AI_EXCL

346102

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

37503

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E4_HYTHY_AI_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 37503 29987 7516
Unadjusted prevalence (%) 10.54 15.11 4.78
Mean age at first event (years) 51.76 49.98 58.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.45 [1.28, 1.65] 1.2e-8 2944
15 years 0.01 1.04 [0.93, 1.17] 4.7e-1 1446
5 years 0.00 1.83 [1.63, 2.05] 6.6e-25 720
1 year 0.00 1.81 [1.48, 2.22] 9.8e-9 127

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 149

Survival analyses between endpoints

Plot

before Hypothyroidism, strict autoimmune
after Hypothyroidism, strict autoimmune

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Drugs most likely to be purchased after Hypothyroidism, strict autoimmune