Hypothyroidism (congenital or acquired)


No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries None


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Check pre-conditions, main-only, mode, ICD version None


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Check minimum number of events None


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Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Hypothyroidism (congenital or acquired) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 43484 34684 8800
Unadjusted prevalence (%) 12.22 17.48 5.59
Mean age at first event (years) 51.65 50.00 58.14


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.51 [1.32, 1.73] 1.3e-9 3291
15 years 0.01 1.05 [0.93, 1.19] 4.0e-1 1603
5 years 0.00 1.86 [1.66, 2.09] 4.3e-26 802
1 year 0.00 1.89 [1.55, 2.30] 1.9e-10 145

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: HYPOTHYROIDISM – Hypothyroidism (congenital or acquired)
GWS hits:

Survival analyses between endpoints


before Hypothyroidism (congenital or acquired)
after Hypothyroidism (congenital or acquired)

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Drugs most likely to be purchased after Hypothyroidism (congenital or acquired)