Hypothyroidism (congenital or acquired)

HYPOTHYROIDISM

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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HYPOTHYROIDISM

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Hypothyroidism (congenital or acquired) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 43484 34684 8800
Unadjusted prevalence (%) 12.22 17.48 5.59
Mean age at first event (years) 51.65 50.00 58.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.51 [1.32, 1.73] 1.3e-9 3291
15 years 0.01 1.05 [0.93, 1.19] 4.0e-1 1603
5 years 0.00 1.86 [1.66, 2.09] 4.3e-26 802
1 year 0.00 1.89 [1.55, 2.30] 1.9e-10 145

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: HYPOTHYROIDISM – Hypothyroidism (congenital or acquired)
GWS hits:

Survival analyses between endpoints

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Plot

before Hypothyroidism (congenital or acquired)
after Hypothyroidism (congenital or acquired)

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Drugs most likely to be purchased after Hypothyroidism (congenital or acquired)

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