Precocious central puberty

E4_PRECOXCENTPUB

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E22.80, E22.88
Hospital discharge: ICD-9 259
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E22.80, E22.88
Cause of death: ICD-9 259
Cause of death: ICD-8 $!$

177

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

171

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Check minimum number of events None

171

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Include endpoints None

171

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E4_PRECOXCENTPUB

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 171 121 50
Unadjusted prevalence (%) 0.05 0.06 0.03
Mean age at first event (years) 15.58 15.22 16.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_PRECOXCENTPUB – Precocious central puberty
GWS hits: 1

Survival analyses between endpoints

Plot

before Precocious central puberty
after Precocious central puberty

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Drugs most likely to be purchased after Precocious central puberty