Vitamin A deficiency

E4_VIT_A_DEF

ascorbic acid deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E50
Hospital discharge: ICD-9 264
Hospital discharge: ICD-8 260
Cause of death: ICD-10 E50
Cause of death: ICD-9 264
Cause of death: ICD-8 260

118

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

111

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Check minimum number of events None

111

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Include endpoints None

111

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E4_VIT_A_DEF

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E50-E64
Name in latin Deficientia vitamini A

Summary Statistics

Key figures

All Female Male
Number of individuals 111 74 37
Unadjusted prevalence (%) 0.03 0.04 0.02
Mean age at first event (years) 50.65 44.73 62.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_VIT_A_DEF – Vitamin A deficiency
GWS hits:

Survival analyses between endpoints

Plot

before Vitamin A deficiency
after Vitamin A deficiency

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Drugs most likely to be purchased after Vitamin A deficiency