Affective disorder, aux endpoint for F5_SAD

F5_ADO

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F25, F30, F31, F32, F33, F34
Hospital discharge: ICD-9 2957A|296|3004A
Hospital discharge: ICD-8 29570|296|30040|30041
Cause of death: ICD-10 F25, F30, F31, F32, F33, F34
Cause of death: ICD-9 2957A|296|3004A
Cause of death: ICD-8 29570|296|30040|30041

44813

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

44813

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Check minimum number of events None

44813

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Include endpoints None

44813

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F5_ADO

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6v3

Summary Statistics

Key figures

All Female Male
Number of individuals 44813 29301 15512
Unadjusted prevalence (%) 12.60 14.77 9.86
Mean age at first event (years) 40.85 39.57 43.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.31 [1.89, 2.81] 1.2e-16 3318
15 years 0.01 1.66 [1.43, 1.94] 7.5e-11 1427
5 years 0.00 2.98 [2.63, 3.37] 3.4e-67 747
1 year 0.00 7.70 [6.62, 8.96] <1e-100 370

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_ADO – Affective disorder, aux endpoint for F5_SAD
GWS hits:

Survival analyses between endpoints

Plot

before Affective disorder, aux endpoint for F5_SAD
after Affective disorder, aux endpoint for F5_SAD

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Drugs most likely to be purchased after Affective disorder, aux endpoint for F5_SAD