Cerebrovascular diseases (FINNGEN)

FG_CEREBVASC

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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FG_CEREBVASC

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Cerebrovascular diseases (FINNGEN) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 26781 10731 16050
Unadjusted prevalence (%) 7.53 5.41 10.20
Mean age at first event (years) 65.65 64.54 66.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.08 [3.61, 4.61] <1e-100 8735
15 years 0.01 1.96 [1.76, 2.17] 2.3e-36 2832
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FG_CEREBVASC – Cerebrovascular diseases (FINNGEN)
GWS hits: 14

Survival analyses between endpoints

Plot

before Cerebrovascular diseases (FINNGEN)
after Cerebrovascular diseases (FINNGEN)

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Drugs most likely to be purchased after Cerebrovascular diseases (FINNGEN)