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Cerebrovascular diseases

DOID EFO MESH SNOMED PheWeb

I9_CEREBVASC

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I60-I69
Cause of death: ICD-10 I60-I69

29116

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

29116

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Check minimum number of events None

29116

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Include endpoints

30737

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I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cerebrovascular diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 30737 12179 18558
Unadjusted prevalence (%) 8.64 6.14 11.79
Mean age at first event (years) 65.71 64.43 66.56

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.44 [4.00, 4.93] <1e-100 9747
15 years 0.01 2.06 [1.86, 2.28] 1.1e-45 3269
5 years 0.01 4.14 [3.82, 4.48] <1e-100 2729
1 year 0.00 19.20 [17.37, 21.23] <1e-100 2963

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CEREBVASC – Cerebrovascular diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Cerebrovascular diseases
after Cerebrovascular diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cerebrovascular diseases

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