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Stroke, including SAH

DOID EFO MESH SNOMED PheWeb

I9_STR_SAH

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I60, I61, I63, I64
Hospital discharge: ICD-9 430|431|4330A|4331A|4339A|4340A|4341A|4349A|436
Hospital discharge: ICD-8 430|431|433|434|436
Hospital discharge: excluded ICD-10 I63.6
Hospital discharge: excluded ICD-8 43101|43191
Cause of death: ICD-10 I60, I61, I63, I64
Cause of death: ICD-9 430|431|4330A|4331A|4339A|4340A|4341A|4349A|436
Cause of death: ICD-8 430|431|433|434|436
Cause of death: excluded ICD-10 I63.6
Cause of death: excluded ICD-8 43101|43191

24778

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

24668

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Check minimum number of events None

24668

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Include endpoints None

24668

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I9_STR_SAH

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 24668 9462 15206
Unadjusted prevalence (%) 6.93 4.77 9.66
Mean age at first event (years) 66.07 65.31 66.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.63 [4.10, 5.23] <1e-100 8403
15 years 0.01 2.05 [1.85, 2.28] 1.2e-41 2705
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_STR_SAH – Stroke, including SAH
GWS hits:

Survival analyses between endpoints

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Plot

before Stroke, including SAH
after Stroke, including SAH

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Stroke, including SAH

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