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Stroke, excluding SAH

DOID EFO MESH SNOMED PheWeb

I9_STR

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I61, I63, I64
Hospital discharge: ICD-9 431|4330A|4331A|4339A|4340A|4341A|4349A|436
Hospital discharge: ICD-8 431|433|434|436
Hospital discharge: excluded ICD-10 I63.6
Hospital discharge: excluded ICD-8 43101|43191
Cause of death: ICD-10 I61, I63, I64
Cause of death: ICD-9 431|4330A|4331A|4339A|4340A|4341A|4349A|436
Cause of death: ICD-8 431|433|434|436
Cause of death: excluded ICD-10 I63.6
Cause of death: excluded ICD-8 43101|43191

23222

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

23110

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Check minimum number of events None

23110

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Include endpoints None

23110

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I9_STR

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 23110 8690 14420
Unadjusted prevalence (%) 6.50 4.38 9.16
Mean age at first event (years) 66.99 66.58 67.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.21 [3.72, 4.76] <1e-100 8020
15 years 0.01 1.89 [1.69, 2.12] 9.9e-28 2599
5 years 0.01 4.01 [3.66, 4.39] <1e-100 2239
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_STR – Stroke, excluding SAH
GWS hits: 2

Survival analyses between endpoints

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Plot

before Stroke, excluding SAH
after Stroke, excluding SAH

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Stroke, excluding SAH

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