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Gout, strict definition

DOID EFO MESH SNOMED PheWeb

GOUT_STRICT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

GOUT_IDIOP_NOS

5892

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Filter registries

Medicine purchases: ATC M04AA01|M04AA03|M04AB01|M04AB03

4571

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Check pre-conditions, main-only, mode, ICD version None

3886

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Check minimum number of events

Min. number of events 3

3886

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Include endpoints None

3886

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GOUT_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 3886 740 3146
Unadjusted prevalence (%) 1.09 0.37 2.00
Mean age at first event (years) 61.94 65.11 61.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.14 [1.60, 2.88] 4.0e-7 983
15 years 0.01 1.54 [1.23, 1.91] 1.2e-4 514
5 years 0.00 2.11 [1.67, 2.66] 3.4e-10 243
1 year 0.00 1.59 [1.07, 2.35] 2.1e-2 34

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GOUT_STRICT – Gout, strict definition
GWS hits: 8

Survival analyses between endpoints

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Plot

before Gout, strict definition
after Gout, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gout, strict definition

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