Gout

M13_GOUT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M10
Hospital discharge: ICD-9 2740
Hospital discharge: ICD-8 2740
Cause of death: ICD-10 M10
Cause of death: ICD-9 2740
Cause of death: ICD-8 2740
KELA reimbursements: KELA codes 212

7704

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7704

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Check minimum number of events None

7704

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Include endpoints None

7704

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M13_GOUT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14

Summary Statistics

Key figures

All Female Male
Number of individuals 7704 1752 5952
Unadjusted prevalence (%) 2.17 0.88 3.78
Mean age at first event (years) 64.50 66.55 63.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.40 [2.75, 4.19] 4.9e-30 2007
15 years 0.01 1.63 [1.36, 1.95] 1.1e-7 707
5 years 0.01 4.06 [3.48, 4.74] 7.5e-71 706
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_GOUT – Gout
GWS hits: 13

Survival analyses between endpoints

Plot

before Gout
after Gout

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