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Polyarthropathies

DOID EFO MESH PheWeb

M13_POLYARTHROPATHIES

obsolete_juvenile idiopathic arthritis: ['A group of chronic, inflammatory childhood disorders of unknown etiology that primarily involve joints.']

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M05-M14
Cause of death: ICD-10 M05-M14

26481

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

26481

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Check minimum number of events None

26481

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Include endpoints

29245

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M13_POLYARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 29245 15698 13547
Unadjusted prevalence (%) 8.22 7.91 8.61
Mean age at first event (years) 52.93 49.33 57.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.45 [2.15, 2.78] 1.5e-41 4119
15 years 0.01 1.47 [1.30, 1.66] 6.7e-10 1703
5 years 0.00 2.94 [2.66, 3.25] 5.8e-98 1162
1 year 0.00 6.53 [5.73, 7.45] <1e-100 520

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLYARTHROPATHIES – Polyarthropathies
GWS hits: 10

Survival analyses between endpoints

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Plot

before Polyarthropathies
after Polyarthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Polyarthropathies

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