Major coronary heart disease event excluding revascularizations

I9_CHD_NOREV

intermediate coronary syndrome: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I20.0, I21, I22
Hospital discharge: ICD-9 410|4110
Hospital discharge: ICD-8 410|4110
Cause of death: ICD-10 I21, I22, I23, I24, I25, I46, R96, R98
Cause of death: ICD-9 41[0-4]|798
Cause of death: ICD-8 41[0-4]|798
Cause of death: excluded ICD-9 7980A

35449

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Check pre-conditions, main-only, mode, ICD version

Check only main diagnosis Yes, side diagnoses are not checked
Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

33398

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Check minimum number of events None

33398

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Include endpoints

33484

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I9_CHD_NOREV

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 33484 9493 23991
Unadjusted prevalence (%) 9.41 4.78 15.24
Mean age at first event (years) 66.69 68.82 65.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.89 [4.40, 5.43] <1e-100 13165
15 years 0.01 2.28 [2.06, 2.51] 4.9e-61 3923
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CHD_NOREV – Major coronary heart disease event excluding revascularizations
GWS hits:

Survival analyses between endpoints

Plot

before Major coronary heart disease event excluding revascularizations
after Major coronary heart disease event excluding revascularizations

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Drugs most likely to be purchased after Major coronary heart disease event excluding revascularizations