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Myocardial infarction

DOID EFO MESH SNOMED PheWeb

I9_MI

myocardial infarction: Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I21, I22
Hospital discharge: ICD-9 410
Hospital discharge: ICD-8 410
Cause of death: ICD-10 I21, I22
Cause of death: ICD-9 410
Cause of death: ICD-8 410

24914

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

24914

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Check minimum number of events None

24914

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Include endpoints None

24914

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I9_MI

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Myocardial infarction based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 24914 6561 18353
Unadjusted prevalence (%) 7.00 3.31 11.66
Mean age at first event (years) 66.48 69.45 65.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.69 [3.26, 4.17] 7.6e-96 9574
15 years 0.01 1.84 [1.66, 2.04] 1.9e-30 3162
5 years 0.00 3.46 [3.18, 3.77] <1e-100 2060
1 year 0.01 27.70 [25.02, 30.67] <1e-100 3430

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_MI – Myocardial infarction
GWS hits:

Survival analyses between endpoints

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Plot

before Myocardial infarction
after Myocardial infarction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Myocardial infarction

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