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Any dementia

DOID MESH PheWeb

KRA_PSY_DEMENTIA

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F00-F09, F05.1, G30
Hospital discharge: ICD-9  290|2912A|2828C|2941A|3310A|3311A|4378A 
Hospital discharge: ICD-8 290
Cause of death: ICD-10 F00-F09, F05.1, G30
Cause of death: ICD-9  290|2912A|2828C|2941A|3310A|3311A|4378A 
Cause of death: ICD-8 290

12513

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

12472

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Check minimum number of events None

12472

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Include endpoints None

12472

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KRA_PSY_DEMENTIA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 12472 5117 7355
Unadjusted prevalence (%) 3.51 2.58 4.67
Mean age at first event (years) 77.89 78.05 77.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 10.52 [9.41, 11.76] <1e-100 6702
15 years 0.02 2.82 [2.49, 3.18] 5.4e-62 1492
5 years 0.01 7.52 [6.86, 8.24] <1e-100 2927
1 year 0.01 18.90 [17.09, 20.90] <1e-100 2257

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_DEMENTIA – Any dementia
GWS hits:

Survival analyses between endpoints

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Plot

before Any dementia
after Any dementia

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