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Crohn disease (strict definition, require KELA)

DOID EFO MESH PheWeb

K11_CD_STRICT

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

K11_KELACROHN

1676

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Filter registries

Hospital Discharge: ICD-10 K50
Hospital discharge: ICD-9 555
Hospital discharge: ICD-8 5630
Cause of death: ICD-10 K50
Cause of death: ICD-9 555
Cause of death: ICD-8 5630

1553

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1553

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Check minimum number of events None

1553

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Include endpoints None

1553

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K11_CD_STRICT

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Morbus Crohn

Summary Statistics

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Key figures

All Female Male
Number of individuals 1553 881 672
Unadjusted prevalence (%) 0.44 0.44 0.43
Mean age at first event (years) 40.13 39.40 41.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.32 [1.37, 3.93] 1.7e-3 47
15 years 0.01 1.82 [1.07, 3.10] 2.8e-2 26
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CD_STRICT – Crohn disease (strict definition, require KELA)
GWS hits:

Survival analyses between endpoints

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Plot

before Crohn disease (strict definition, require KELA)
after Crohn disease (strict definition, require KELA)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Crohn disease (strict definition, require KELA)

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