IBD patients in KELA-register

K11_KELAIBD

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

KELA reimbursements: KELA codes 208|209

6962

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Check pre-conditions, main-only, mode, ICD version None

6962

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Check minimum number of events None

6962

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Include endpoints None

6962

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K11_KELAIBD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to IBD patients in KELA-register based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 6962 3651 3311
Unadjusted prevalence (%) 1.96 1.84 2.10
Mean age at first event (years) 40.25 38.02 42.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.29 [0.91, 1.83] 1.6e-1 356
15 years 0.01 0.93 [0.68, 1.28] 6.7e-1 151
5 years 0.00 1.61 [1.17, 2.22] 3.4e-3 66
1 year 0.00 2.88 [1.79, 4.64] 1.3e-5 21

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_KELAIBD – IBD patients in KELA-register
GWS hits: 39

Survival analyses between endpoints

Plot

before IBD patients in KELA-register
after IBD patients in KELA-register

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Drugs most likely to be purchased after IBD patients in KELA-register