UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

K11_KELAUC

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

KELA reimbursements: KELA codes 208
KELA reimbursements: ICD-10 K51

6962

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Check pre-conditions, main-only, mode, ICD version None

4178

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Check minimum number of events None

4178

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Include endpoints

5245

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K11_KELAUC

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5245 2682 2563
Unadjusted prevalence (%) 1.47 1.35 1.63
Mean age at first event (years) 40.06 37.46 42.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.92 [0.60, 1.40] 6.9e-1 296
15 years 0.00 0.69 [0.48, 1.01] 5.4e-2 122
5 years 0.00 1.22 [0.83, 1.78] 3.1e-1 52
1 year 0.00 2.41 [1.42, 4.07] 1.1e-3 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_KELAUC – UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)
GWS hits:

Survival analyses between endpoints

Plot

before UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)
after UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

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Drugs most likely to be purchased after UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)