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Alogoneurodystrophy

DOID EFO MESH SNOMED PheWeb

M13_ALGONEURO

reflex sympathetic dystrophy: Complex regional pain syndrome type 1 (CRPS1) is a form of complex regional pain syndrome (see this term) in which the pain is disproportionate to any known inciting event and is characterized by continuous pain, allodynia, or hyperalgesia as well as edema, coloration (changes in skin blood flow), or abnormal sudomotor activity in the region of pain. Onset of CRPS1 symptoms may occur within a few days to a month after an injury or trauma to the affected limb.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M89.0
Hospital discharge: ICD-9 7337
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M89.0
Cause of death: ICD-9 7337
Cause of death: ICD-8 $!$

813

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

813

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Check minimum number of events None

813

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Include endpoints None

813

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M13_ALGONEURO

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M89
Name in latin Algoneurodystrophia

Summary Statistics

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Key figures

All Female Male
Number of individuals 813 615 198
Unadjusted prevalence (%) 0.23 0.31 0.13
Mean age at first event (years) 47.18 46.16 50.34

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.46 [0.59, 3.62] 4.2e-1 33
15 years 0.01 1.17 [0.51, 2.65] 7.1e-1 16
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ALGONEURO – Alogoneurodystrophy
GWS hits: 1

Survival analyses between endpoints

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Plot

before Alogoneurodystrophy
after Alogoneurodystrophy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alogoneurodystrophy

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