Arthropathies in other diseases classified elsewhere

M13_ARTHINOTH

arthritis: An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M14*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M14*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

965

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

965

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Check minimum number of events None

965

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Include endpoints None

965

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M13_ARTHINOTH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 965 528 437
Unadjusted prevalence (%) 0.27 0.27 0.28
Mean age at first event (years) 53.79 51.82 56.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.72 [2.05, 10.88] 2.7e-4 152
15 years 0.02 2.73 [1.13, 6.56] 2.5e-2 74
5 years 0.01 6.35 [3.48, 11.56] 1.6e-9 53
1 year 0.00 10.83 [5.52, 21.25] 4.3e-12 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_ARTHINOTH – Arthropathies in other diseases classified elsewhere
GWS hits: 1

Survival analyses between endpoints

Plot

before Arthropathies in other diseases classified elsewhere
after Arthropathies in other diseases classified elsewhere

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Drugs most likely to be purchased after Arthropathies in other diseases classified elsewhere