Disorders of continuity of bone

M13_BONECONTINUITY

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M84
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M84
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

2231

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2231

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Check minimum number of events None

2231

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Include endpoints None

2231

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M13_BONECONTINUITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M80-M85
Name in latin Perturbationes continuitatis ossis

Summary Statistics

Key figures

All Female Male
Number of individuals 2231 1418 813
Unadjusted prevalence (%) 0.63 0.71 0.52
Mean age at first event (years) 51.44 52.12 50.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.50 [1.26, 9.72] 1.6e-2 173
15 years 0.01 2.06 [0.98, 4.32] 5.5e-2 62
5 years 0.01 4.36 [2.69, 7.07] 2.4e-9 47
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_BONECONTINUITY – Disorders of continuity of bone
GWS hits:

Survival analyses between endpoints

Plot

before Disorders of continuity of bone
after Disorders of continuity of bone

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Drugs most likely to be purchased after Disorders of continuity of bone