Palmar fascial fibromatosis [Dupuytren]

M13_DUPUTRYEN

Plantar Fibromatosis: A superficial fibromatosis arising from soft tissue of the plantar regions. It is characterized by the presence of spindle-shaped fibroblasts, hypercellularity, and an infiltrative growth pattern.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M72.0
Hospital discharge: ICD-9 7286
Hospital discharge: ICD-8 7339
Cause of death: ICD-10 M72.0
Cause of death: ICD-9 7286
Cause of death: ICD-8 7339

4822

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4750

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Check minimum number of events None

4750

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Include endpoints None

4750

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M13_DUPUTRYEN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M72
Name in latin Fibromatosis aponeurosis palmaris

Summary Statistics

Key figures

All Female Male
Number of individuals 4750 1208 3542
Unadjusted prevalence (%) 1.34 0.61 2.25
Mean age at first event (years) 55.76 50.95 57.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.11 [0.85, 1.44] 4.5e-1 944
15 years 0.01 0.91 [0.74, 1.12] 3.8e-1 482
5 years 0.00 1.16 [0.95, 1.41] 1.6e-1 169
1 year 0.00 1.37 [0.96, 1.95] 8.3e-2 36

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_DUPUTRYEN – Palmar fascial fibromatosis [Dupuytren]
GWS hits: 37

Survival analyses between endpoints

Plot

before Palmar fascial fibromatosis [Dupuytren]
after Palmar fascial fibromatosis [Dupuytren]

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Drugs most likely to be purchased after Palmar fascial fibromatosis [Dupuytren]