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Soft tissue disorders

DOID EFO MESH SNOMED PheWeb

M13_SOFTTISSUE

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M60-M79
Cause of death: ICD-10 M60-M79

86981

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

86981

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Check minimum number of events None

86981

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Include endpoints

92404

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M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Soft tissue disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 92404 54360 38044
Unadjusted prevalence (%) 25.97 27.40 24.17
Mean age at first event (years) 51.02 49.33 53.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.40 [1.27, 1.54] 4.1e-12 6960
15 years 0.01 1.02 [0.94, 1.10] 7.1e-1 3234
5 years 0.00 1.65 [1.52, 1.79] 7.6e-34 1520
1 year 0.00 3.49 [3.10, 3.93] 2.1e-93 592

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SOFTTISSUE – Soft tissue disorders
GWS hits: 15

Survival analyses between endpoints

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Plot

before Soft tissue disorders
after Soft tissue disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Soft tissue disorders

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