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Multifocal fibrosclerosis

DOID EFO MESH SNOMED PheWeb

M13_MULTIFIBRO

multiple sclerosis: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M35.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M35.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

154

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

154

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Check minimum number of events None

154

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Include endpoints None

154

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M13_MULTIFIBRO

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M35
Name in latin Fibrosclerosis multifocalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 154 103 51
Unadjusted prevalence (%) 0.04 0.05 0.03
Mean age at first event (years) 61.02 58.57 65.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MULTIFIBRO – Multifocal fibrosclerosis
GWS hits:

Survival analyses between endpoints

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Plot

before Multifocal fibrosclerosis
after Multifocal fibrosclerosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Multifocal fibrosclerosis

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