Other systemic involvement of connective tissue

M13_OTHCONN

connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M35
Cause of death: ICD-10 M35

7686

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7686

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Check minimum number of events None

7686

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M13_OTHCONN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30-M36
Name in latin Aliae morbositates systemicae textus connectivi

Similar endpoints

List of similar endpoints to Other systemic involvement of connective tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 8056 5943 2113
Unadjusted prevalence (%) 2.26 3.00 1.34
Mean age at first event (years) 56.09 53.42 63.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.33 [1.72, 3.17] 5.9e-8 886
15 years 0.01 1.31 [1.02, 1.68] 3.7e-2 357
5 years 0.00 3.01 [2.51, 3.60] 4.2e-33 286
1 year 0.00 6.75 [5.43, 8.39] 3.6e-66 137

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_OTHCONN – Other systemic involvement of connective tissue
GWS hits:

Survival analyses between endpoints

Plot

before Other systemic involvement of connective tissue
after Other systemic involvement of connective tissue

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Drugs most likely to be purchased after Other systemic involvement of connective tissue