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Paget disease

DOID EFO MESH SNOMED PheWeb

M13_PAGET

osteitis deformans: A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M88
Hospital discharge: ICD-9 7310
Hospital discharge: ICD-8 72199
Cause of death: ICD-10 M88
Cause of death: ICD-9 7310
Cause of death: ICD-8 72199

2376

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

105

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Check minimum number of events None

105

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Include endpoints None

105

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M13_PAGET

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M86-M90
Name in latin Osteitis deformans Paget

Summary Statistics

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Key figures

All Female Male
Number of individuals 105 48 57
Unadjusted prevalence (%) 0.03 0.02 0.04
Mean age at first event (years) 63.18 61.81 64.33

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_PAGET – Paget disease
GWS hits:

Survival analyses between endpoints

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Plot

before Paget disease
after Paget disease

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