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Scoliosis

DOID EFO MESH SNOMED PheWeb

M13_SCOLIOSIS

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M41
Hospital discharge: ICD-9 7373
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M41
Cause of death: ICD-9 7373
Cause of death: ICD-8 $!$

2337

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2331

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Check minimum number of events None

2331

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Include endpoints None

2331

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M13_SCOLIOSIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M40-M43
Name in latin Scoliosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2331 1819 512
Unadjusted prevalence (%) 0.66 0.92 0.33
Mean age at first event (years) 40.87 40.72 41.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.68 [0.83, 3.41] 1.5e-1 77
15 years 0.01 0.90 [0.43, 1.91] 7.9e-1 29
5 years 0.00 2.50 [1.45, 4.32] 1.0e-3 28
1 year 0.00 4.29 [2.05, 8.97] 1.1e-4 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SCOLIOSIS – Scoliosis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Scoliosis
after Scoliosis

loading spinner Loading survival analyses plot