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Deforming dorsopathies

DOID EFO MESH SNOMED PheWeb

M13_DEFORMDORSO

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M40-M43
Cause of death: ICD-10 M40-M43

7981

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7981

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Check minimum number of events None

7981

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Include endpoints

8749

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M13_DEFORMDORSO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Deforming dorsopathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 8749 5853 2896
Unadjusted prevalence (%) 2.46 2.95 1.84
Mean age at first event (years) 48.42 48.07 49.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.09 [1.54, 2.82] 1.8e-6 441
15 years 0.01 1.34 [1.04, 1.74] 2.4e-2 200
5 years 0.00 2.24 [1.74, 2.89] 5.3e-10 117
1 year 0.00 3.47 [2.38, 5.05] 9.2e-11 35

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_DEFORMDORSO – Deforming dorsopathies
GWS hits: 4

Survival analyses between endpoints

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Plot

before Deforming dorsopathies
after Deforming dorsopathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Deforming dorsopathies

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