Deforming dorsopathies


scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M40-M43
Cause of death: ICD-10 M40-M43


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Deforming dorsopathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 8749 5853 2896
Unadjusted prevalence (%) 2.46 2.95 1.84
Mean age at first event (years) 48.42 48.07 49.13


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.09 [1.54, 2.82] 1.8e-6 441
15 years 0.01 1.34 [1.04, 1.74] 2.4e-2 200
5 years 0.00 2.24 [1.74, 2.89] 5.3e-10 117
1 year 0.00 3.47 [2.38, 5.05] 9.2e-11 35

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_DEFORMDORSO – Deforming dorsopathies
GWS hits: 4

Survival analyses between endpoints


before Deforming dorsopathies
after Deforming dorsopathies

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Drugs most likely to be purchased after Deforming dorsopathies