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Disorders of muscles

DOID EFO MESH SNOMED PheWeb

M13_MUSCLE

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M60-M63
Cause of death: ICD-10 M60-M63

2209

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2209

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Check minimum number of events None

2209

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Include endpoints

2722

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M13_MUSCLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of muscles based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2722 1446 1276
Unadjusted prevalence (%) 0.77 0.73 0.81
Mean age at first event (years) 49.21 47.70 50.92

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.12 [1.24, 3.63] 5.9e-3 267
15 years 0.01 1.27 [0.82, 1.95] 2.8e-1 101
5 years 0.00 2.57 [1.80, 3.67] 2.4e-7 69
1 year 0.00 9.97 [6.78, 14.66] 1.6e-31 52

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCLE – Disorders of muscles
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders of muscles
after Disorders of muscles

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Drugs most likely to be purchased after Disorders of muscles

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