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Spinal stenosis

DOID EFO MESH SNOMED PheWeb

M13_SPINSTENOSIS

spinal stenosis: Narrowing of the spinal canal.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M48.0
Hospital discharge: ICD-9 7230A|7240
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M48.0
Cause of death: ICD-9 7230A|7240
Cause of death: ICD-8 $!$

17160

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

17093

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Check minimum number of events None

17093

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Include endpoints None

17093

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M13_SPINSTENOSIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M48
Name in latin Stenosis spinalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 17093 8943 8150
Unadjusted prevalence (%) 4.80 4.51 5.18
Mean age at first event (years) 64.07 63.67 64.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.79 [1.50, 2.13] 8.2e-11 2080
15 years 0.01 1.23 [1.06, 1.43] 7.1e-3 1090
5 years 0.00 1.88 [1.64, 2.15] 4.3e-20 560
1 year 0.00 2.93 [2.41, 3.57] 8.5e-27 161

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SPINSTENOSIS – Spinal stenosis
GWS hits: 25

Survival analyses between endpoints

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Plot

before Spinal stenosis
after Spinal stenosis

loading spinner Loading survival analyses plot