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Mucosal proctocolitis

DOID EFO MESH SNOMED PheWeb

MUCOPROCT

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K51.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K51.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

3670

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3670

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Check minimum number of events None

3670

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Include endpoints None

3670

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MUCOPROCT

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Proctocolitis mucosalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 3670 1855 1815
Unadjusted prevalence (%) 1.03 0.93 1.15
Mean age at first event (years) 44.87 42.49 47.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.76 [0.90, 3.44] 1.0e-1 174
15 years 0.01 1.40 [0.84, 2.34] 2.0e-1 93
5 years 0.00 2.24 [1.43, 3.53] 4.7e-4 42
1 year 0.00 5.18 [2.97, 9.05] 7.3e-9 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MUCOPROCT – Mucosal proctocolitis
GWS hits: 24

Survival analyses between endpoints

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Plot

before Mucosal proctocolitis
after Mucosal proctocolitis

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Drugs most likely to be purchased after Mucosal proctocolitis

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