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Other (seronegative) rheumatoid arthritis, wide

DOID EFO MESH SNOMED PheWeb

RHEUMA_OTHER_WIDE

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M06
Hospital discharge: ICD-9 7140B|7148|7142
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M06
Cause of death: ICD-9 7140B|7148|7142
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

5600

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RHEUMA_OTHER_WIDE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14
Name in latin Alia arthritis rheumatoides

Summary Statistics

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Key figures

All Female Male
Number of individuals 5600 3811 1789
Unadjusted prevalence (%) 1.57 1.92 1.14
Mean age at first event (years) 54.99 52.98 59.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.03 [1.43, 2.87] 7.2e-5 726
15 years 0.01 1.29 [0.98, 1.70] 7.2e-2 307
5 years 0.00 2.64 [2.11, 3.30] 1.9e-17 203
1 year 0.00 6.72 [5.16, 8.75] 1.8e-45 100

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_OTHER_WIDE – Other (seronegative) rheumatoid arthritis, wide
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other (seronegative) rheumatoid arthritis, wide
after Other (seronegative) rheumatoid arthritis, wide

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other (seronegative) rheumatoid arthritis, wide

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