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Adult-onset Still disease

DOID EFO MESH SNOMED PheWeb

STILL_ADULT

adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M06.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M06.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

100

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

100

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Check minimum number of events None

100

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Include endpoints None

100

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STILL_ADULT

Extra metadata

First used in FinnGen datafreeze DF5
Parent code in ICD-10 M06
Name in latin Arthritis rheumatoides seronegativa

Summary Statistics

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Key figures

All Female Male
Number of individuals 100 60 40
Unadjusted prevalence (%) 0.03 0.03 0.03
Mean age at first event (years) 48.55 44.72 54.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: STILL_ADULT – Adult-onset Still disease
GWS hits:

Survival analyses between endpoints

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Plot

before Adult-onset Still disease
after Adult-onset Still disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Adult-onset Still disease

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