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Type 1 diabetes, wide definition, subgroup 1

DOID EFO MESH SNOMED PheWeb

T1D_WIDE1

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not PANCREATITIS
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST
and INSULIN_INTER_AND_LONG

10848

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

7660

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T1D_WIDE1

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 7660 3702 3958
Unadjusted prevalence (%) 2.15 1.87 2.52
Mean age at first event (years) 28.89 27.15 30.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.53 [1.93, 3.32] 2.3e-11 755
15 years 0.01 1.82 [1.46, 2.28] 1.3e-7 328
5 years 0.00 0.94 [0.65, 1.36] 7.6e-1 38
1 year 0.00 1.47 [0.77, 2.82] 2.5e-1 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_WIDE1 – Type 1 diabetes, wide definition, subgroup 1
GWS hits:

Survival analyses between endpoints

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Plot

before Type 1 diabetes, wide definition, subgroup 1
after Type 1 diabetes, wide definition, subgroup 1

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Drugs most likely to be purchased after Type 1 diabetes, wide definition, subgroup 1

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