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Type 1 diabetes, strict definition, subgroup 1

DOID EFO MESH SNOMED PheWeb

T1D_STRICT1

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not E4_DM2
and not PANCREATITIS
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST
and INSULIN_INTER_AND_LONG

3474

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version

Pre-conditions EVENT_AGE<40

0

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Check minimum number of events None

0

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Include endpoints

3116

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T1D_STRICT1

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3116 1571 1545
Unadjusted prevalence (%) 0.88 0.79 0.98
Mean age at first event (years) 15.24 14.81 15.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.89 [2.92, 8.19] 1.6e-9 58
15 years 0.04 6.27 [3.59, 10.94] 1.0e-10 32
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_STRICT1 – Type 1 diabetes, strict definition, subgroup 1
GWS hits: 30

Survival analyses between endpoints

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Plot

before Type 1 diabetes, strict definition, subgroup 1
after Type 1 diabetes, strict definition, subgroup 1

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 1 diabetes, strict definition, subgroup 1

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