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Ulcerative enterocolitis

DOID EFO MESH SNOMED PheWeb

ULCERENTER

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K51.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K51.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

850

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

850

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Check minimum number of events None

850

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Include endpoints None

850

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ULCERENTER

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Enterocolitis ulcerosa [chronica]

Summary Statistics

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Key figures

All Female Male
Number of individuals 850 442 408
Unadjusted prevalence (%) 0.24 0.22 0.26
Mean age at first event (years) 44.11 39.66 48.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.96 [2.97, 8.29] 9.5e-10 78
15 years 0.02 2.26 [1.24, 4.11] 7.5e-3 30
5 years 0.01 3.99 [2.20, 7.24] 5.0e-6 23
1 year 0.00 9.99 [4.74, 21.04] 1.4e-9 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ULCERENTER – Ulcerative enterocolitis
GWS hits: 3

Survival analyses between endpoints

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Plot

before Ulcerative enterocolitis
after Ulcerative enterocolitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative enterocolitis

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