Other ulcerative colitis

ULCEROTH

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K51.8
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K51.8
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1493

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1493

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Check minimum number of events None

1493

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Include endpoints None

1493

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ULCEROTH

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Alia colitis ulcerosa specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 1493 807 686
Unadjusted prevalence (%) 0.42 0.41 0.44
Mean age at first event (years) 45.05 42.76 47.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.16 [1.36, 3.44] 1.1e-3 100
15 years 0.01 1.19 [0.71, 1.98] 5.1e-1 46
5 years 0.00 1.63 [0.89, 2.98] 1.1e-1 19
1 year 0.00 8.74 [4.76, 16.04] 2.5e-12 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ULCEROTH – Other ulcerative colitis
GWS hits: 2

Survival analyses between endpoints

Plot

before Other ulcerative colitis
after Other ulcerative colitis

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Drugs most likely to be purchased after Other ulcerative colitis