≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Diabetic neuropathy

DOID EFO MESH SNOMED PheWeb

DM_NEUROPATHY

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E1[0-4]4
Hospital discharge: ICD-9 2505
Hospital discharge: ICD-8 25005
Cause of death: ICD-10 E1[0-4]4
Cause of death: ICD-9 2505
Cause of death: ICD-8 25005

-

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

-

diagram downward connector

Check minimum number of events None

-

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

2507

diagram downward connector
DM_NEUROPATHY

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

↥

List of similar endpoints to Diabetic neuropathy based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2507 895 1612
Unadjusted prevalence (%) 0.70 0.45 1.02
Mean age at first event (years) 56.91 54.11 58.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.93 [2.98, 5.19] 2.9e-22 694
15 years 0.01 2.17 [1.75, 2.70] 3.0e-12 299
5 years 0.00 3.73 [3.00, 4.63] 9.4e-33 202
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: DM_NEUROPATHY – Diabetic neuropathy
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Diabetic neuropathy
after Diabetic neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic neuropathy

↥