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Familial hypercholesterolemia, with ichemic heart disease

PheWeb

E4_FH_IHD

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

I9_IHD

58578

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

2562

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E4_FH_IHD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6v3

Summary Statistics

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Key figures

All Female Male
Number of individuals 2562 831 1731
Unadjusted prevalence (%) 0.72 0.42 1.10
Mean age at first event (years) 66.32 67.37 65.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.59 [2.63, 4.90] 7.1e-16 625
15 years 0.01 1.97 [1.45, 2.68] 1.6e-5 312
5 years 0.00 3.59 [2.82, 4.57] 2.7e-25 197
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_FH_IHD – Familial hypercholesterolemia, with ichemic heart disease
GWS hits: 10

Survival analyses between endpoints

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Plot

before Familial hypercholesterolemia, with ichemic heart disease
after Familial hypercholesterolemia, with ichemic heart disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Familial hypercholesterolemia, with ichemic heart disease

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