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Felty syndrome

DOID EFO MESH SNOMED PheWeb

FELTY

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M05.0
Hospital discharge: ICD-9 7141
Hospital discharge: ICD-8 71210
Cause of death: ICD-10 M05.0
Cause of death: ICD-9 7141
Cause of death: ICD-8 71210

150

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

144

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Check minimum number of events None

144

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Include endpoints None

144

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FELTY

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05
Name in latin Syndroma Felty

Summary Statistics

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Key figures

All Female Male
Number of individuals 144 103 41
Unadjusted prevalence (%) 0.04 0.05 0.03
Mean age at first event (years) 58.64 58.35 59.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FELTY – Felty syndrome
GWS hits:

Survival analyses between endpoints

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Plot

before Felty syndrome
after Felty syndrome

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