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Extrapyramidal and movement disorders

DOID EFO MESH SNOMED PheWeb

G6_XTRAPYR

basal ganglia disease: A disease involving the basal ganglia.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G20-G26
Cause of death: ICD-10 G20-G26

8274

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8274

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Check minimum number of events None

8274

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Include endpoints

8869

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G6_XTRAPYR

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 8869 4451 4418
Unadjusted prevalence (%) 2.49 2.24 2.81
Mean age at first event (years) 60.42 57.96 62.91

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.32 [2.58, 4.29] 2.3e-20 1651
15 years 0.01 2.01 [1.67, 2.42] 1.6e-13 808
5 years 0.00 3.16 [2.70, 3.71] 8.7e-46 532
1 year 0.00 4.42 [3.59, 5.43] 5.2e-45 152

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_XTRAPYR – Extrapyramidal and movement disorders
GWS hits: 1

Survival analyses between endpoints

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Plot

before Extrapyramidal and movement disorders
after Extrapyramidal and movement disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Extrapyramidal and movement disorders

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