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Atherosclerosis, excluding cerebral, coronary and PAD

DOID EFO MESH SNOMED PheWeb

I9_ATHSCLE

atherosclerosis: Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I70
Hospital discharge: ICD-9 440|4370|4371X
Hospital discharge: ICD-8 440
Cause of death: ICD-10 I70
Cause of death: ICD-9 440|4370|4371X
Cause of death: ICD-8 440

13795

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13787

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Check minimum number of events None

13787

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Include endpoints None

13787

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I9_ATHSCLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I70-I79
Name in latin Atherosclerosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 13787 3984 9803
Unadjusted prevalence (%) 3.88 2.01 6.23
Mean age at first event (years) 68.20 68.65 68.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.96 [3.47, 4.52] 2.1e-93 5571
15 years 0.01 2.10 [1.89, 2.33] 3.5e-43 2222
5 years 0.01 3.83 [3.47, 4.23] <1e-100 1769
1 year 0.00 11.96 [10.65, 13.42] <1e-100 1176

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_ATHSCLE – Atherosclerosis, excluding cerebral, coronary and PAD
GWS hits: 15

Survival analyses between endpoints

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Plot

before Atherosclerosis, excluding cerebral, coronary and PAD
after Atherosclerosis, excluding cerebral, coronary and PAD

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Atherosclerosis, excluding cerebral, coronary and PAD

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