Diseases of arteries, arterioles and capillaries (FINNGEN)

FG_DOAAC

vascular disease: A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma.

Endpoint definition

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FinnGen phenotype data

356077 individuals

Apply sex-specific rule None

356077

Check conditions None

356077

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_ATHSCLE

I9_AORTDIS

I9_AORTANEUR

I9_OTHANEUR

I9_ARTEMBTHR

I9_ARTEMBTHRLOW

I9_EMBTHROAOR

20320

FG_DOAAC

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

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Similar endpoints

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List of similar endpoints to Diseases of arteries, arterioles and capillaries (FINNGEN) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	20320	5393	14927
Unadjusted prevalence (%)	5.71	2.72	9.48
Mean age at first event (years)	67.39	67.13	67.49

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	4.94 [4.42, 5.52]	<1e-100	7272
15 years	0.02	2.47 [2.25, 2.71]	1.7e-78	2828
5 years	0.01	4.36 [4.03, 4.72]	<1e-100	2203
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_DOAAC – Diseases of arteries, arterioles and capillaries (FINNGEN)
GWS hits: 15

Survival analyses between endpoints

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Plot

before Diseases of arteries, arterioles and capillaries (FINNGEN)
after Diseases of arteries, arterioles and capillaries (FINNGEN)

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Table

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Drugs most likely to be purchased after Diseases of arteries, arterioles and capillaries (FINNGEN)

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≡ Risteys

R8

R7

R6

R5

R4

R3